FDA status & evidence

GHRP-6: FDA Status and Evidence

A growth hormone releasing peptide on FDA's Category 2 list for 503B compounding. It is not FDA-approved; the clearest human effect is increased growth hormone and appetite.

Medically reviewed by Charles Kamen, MD, board-certified neurologist · ·

What the research shows

GHRP-6 raises growth hormone and, through the ghrelin receptor, strongly increases appetite. Human data are limited to short-term physiology studies. There are no outcome trials for anti-aging, body composition or recovery.

It is on the World Anti-Doping Agency prohibited list.

Frequently Asked Questions

Is GHRP-6 FDA-approved?

No. GHRP-6 is not an FDA-approved drug.

Can a pharmacy compound GHRP-6?

FDA lists GHRP-6 in Category 2 for 503B outsourcing facilities, a list of substances that may present significant safety risks. Check the live FDA lists, which change.

Why does GHRP-6 increase hunger?

It activates the ghrelin receptor, the same receptor behind normal hunger signals.

Selected Research

Peer-reviewed sources on GHRP-6. Research does not constitute a treatment recommendation; appropriateness is determined only after a medical evaluation.

  1. Bowers CY, et al. J Clin Endocrinol Metab. 1990;70(4):975-982. (GH-releasing peptide stimulates GH release, synergy with GHRH).