FDA status & evidence

IGF-1 LR3: FDA Status and Evidence

A long-acting research analog of IGF-1 with no FDA-approved form. It has no human clinical-trial evidence; the approved IGF-1 drug is a different molecule.

Medically reviewed by Charles Kamen, MD, board-certified neurologist ·

What the research shows

IGF-1 LR3 is a modified form of IGF-1 made to last longer in the body. It is used in laboratory research. There are no human clinical trials. The approved IGF-1 drug, mecasermin, is prescribed only for severe primary IGF-1 deficiency and carries warnings for low blood sugar.

It is on the World Anti-Doping Agency prohibited list.

Frequently Asked Questions

Is IGF-1 LR3 FDA-approved?

No. Only mecasermin, a different IGF-1 product, is FDA-approved, and only for severe primary IGF-1 deficiency.

Can a pharmacy compound IGF-1 LR3?

It is not on FDA's bulk-substance lists for compounding.

Has IGF-1 LR3 been tested in humans?

No human clinical trials have been published.