PRP Therapy for Joints
Platelet-rich plasma (PRP) therapy is a regenerative medicine approach that uses the body's own growth factors to support tissue healing. Dr. Charles Kamen, MD, board-certified neurologist at LiveNow Longevity in Las Vegas, offers PRP therapy for joint health applications. Individual results vary.
What Is PRP Therapy
PRP is prepared from the patient's own blood by centrifuging to concentrate platelets. Platelets contain alpha granules filled with growth factors that initiate and accelerate tissue repair. [1] The concentrated platelet solution is injected into damaged or degenerated tissues to stimulate healing.
How PRP Promotes Healing
PRP works by delivering high concentrations of growth factors directly to injured tissue:
- PDGF (Platelet-Derived Growth Factor): stimulates cell replication and blood vessel formation
- TGF-β (Transforming Growth Factor Beta): regulates cell growth and differentiation
- VEGF (Vascular Endothelial Growth Factor): promotes new blood vessel formation
- EGF (Epidermal Growth Factor): supports cell proliferation and tissue repair
- FGF (Fibroblast Growth Factor): supports connective tissue repair
PRP for Joint Applications
PRP is used for various joint conditions:
- Osteoarthritis (knee, hip, shoulder, ankle)
- Rotator cuff injuries and partial tears
- Tennis elbow and golfer's elbow
- Patellar tendinitis
- Plantar fasciitis
- Labral tears (shoulder and hip)
- Cartilage damage and early-stage degeneration
Evidence for Joint Applications
Clinical research supports PRP for osteoarthritis and tendinopathy. Multiple studies show PRP injections reduce pain and improve function in knee osteoarthritis compared to placebo or hyaluronic acid injections. [2] Results are generally more favorable in early-stage degeneration than in advanced arthritis.
PRP Treatment Protocol
PRP therapy involves several steps:
- Blood draw (similar to routine lab work)
- Centrifugation to separate and concentrate platelets
- Injection into the target tissue under ultrasound guidance
- Post-injection rest and activity modification
- Follow-up assessment and potential additional injections
Key Takeaways
- PRP uses concentrated platelets from your own blood to promote healing
- Growth factors stimulate tissue repair in joints and soft tissues
- Used for osteoarthritis, tendinitis, and soft tissue injuries
- Evidence supports effectiveness, especially in early-stage conditions
- Series of injections typically provides best results
- Dr. Kamen uses ultrasound guidance for precise delivery
Common Questions
Is PRP the same as stem cell therapy?
No. PRP uses platelets and their growth factors; stem cell therapy uses living cells with different regenerative potential. Both are forms of regenerative medicine.
How many PRP injections will I need?
Treatment protocols vary. Some patients respond to a single injection; others benefit from a series of 2-3 injections spaced several weeks apart. Dr. Kamen develops individualized plans.
Does PRP hurt?
PRP injections can cause temporary discomfort at the injection site. Local anesthetic is often used to minimize pain during the procedure.
How long until I notice results from PRP?
Some patients notice improvement within weeks; others require 2-3 months to experience full benefits. Healing is a gradual process.
Can PRP help with advanced arthritis?
PRP is most effective in early to moderate arthritis. Advanced degeneration may respond less dramatically. Dr. Kamen evaluates whether PRP is appropriate for your specific condition.
Is PRP covered by insurance?
Most insurance plans consider PRP experimental for joint applications and do not cover it. Our office can provide cost information and discuss payment options.
PRP therapy offers a regenerative approach to joint health using the body's own healing factors. Consult with Dr. Kamen to determine whether PRP therapy is appropriate for your joint condition.
References
- Marx RE. J Oral Maxillofac Surg. 2024;82(4):321-338.
- Bennell KL, et al. Br J Sports Med. 2024;58(9):517-527.
- Huang PH, et al. Am J Sports Med. 2025;53(2):452-463.
- Andia I, et al. Expert Opin Biol Ther. 2024;24(6):523-537.